Researchers have found a link between depression and bacteria in our mouth. The mouth contains different types of microbes, particularly bacteria, that help us keep healthy. Now, a new study has uncovered a potential link between a lack of diversity in oral bacteria and depression. This new study could help us understand depression better and find new ways to overcome it. According to BMC Oral health, a new study has found that individuals with depression tend to have lower diversity of microbes in their mouth. The findings suggest that the diversity of the oral microbiome is negatively correlated with depressive symptoms.

Analysing how depression links with oral microbiome

Depression is a serious and prevalent mental health disorder affecting millions worldwide. A new study has explored the relationship between depression and oral microbiome diversity using data from the National Health and Nutrition Examination Survey (NHANES). The research seeks to address the current knowledge gap and potentially identify new therapeutic targets for depression. Understanding the link between the oral microbiome and depression could lead to innovative approaches to managing this complex mental health disorder. The oral microbiome is a community of bacteria in the mouth that helps with our immune system and overall health. Changes in our oral microbiome have been linked with cardiovascular disease, diabetes, and gastrointestinal disorders. Some studies suggest it may be associated with mood disorders as well.

Methods used by researchers

The study analysed data from the National Health and Nutrition Examination Survey (2009-2012) to explore the connection between depression and oral microbiome diversity. The research involved examining bacterial diversity in the mouth and its potential link to depression symptoms. The researchers used gene sequencing to profile the oral microbiome, considering smoking, alcohol consumption, and oral treatment. They also found differences across gender and racial groups.

Final analysis of the study

NHANES data covered the periods of 2009–2010 and 2011–2012; and the inclusion criteria were:(1) Participants aged 18 years or older(2) Completed the PHQ-9 questionnaire(3) Participated in the oral microbiome data collectionThe final analysis of the study included 15,018 participants, with an average age of 42.2 years. Those with depression were more likely to be younger than 60, female, obese, smokers, and have conditions like hypertension or diabetes.Also read | The link between coffee and healthy aging: what research says