Asia-Pacific markets are set for a lower open, tracking Wall Street losses as uncertainty around the U.S. economy continued to weigh on equities.

Australia’s S&P/ASX 200 traded flat at the open.

Japan’s Nikkei 225 futures pointed to a lower open for the market after returning from a holiday. The futures contract in Chicago is currently at 37,490 and its counterpart in Osaka last traded at 37,450 compared to the index’s previous close of 37,751.88.

Hong Kong’s Hang Seng index futures were at 24,065 also weaker than the HSI’s last close of 24,219.95.

Japan’s headline inflation rose 3.7% year on year in February, easing from a two-year high of 4% seen in January.

U.S. stock futures traded around the flatline after an attempt at extending Wednesday’s Federal Reserve-fueled rally sputtered.

Overnight in the U.S., the S&P 500 slipped 0.22%, thwarting the market’s attempts at recovery from a monthlong rout to close at 5,662.89. The Nasdaq Composite slid 0.33% to end the day at 17,691.63, weighed down by losses in Apple and Alphabet. The Dow Jones Industrial Average inched down 11.31 points, or 0.03%, and closed at 41,953.32.

—CNBC’s Sean Conlon and Brian Evans contributed to this report.